BRAFV600E-Mutant Melanoma Presenting With Cardiac Involvement
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چکیده
منابع مشابه
Hypereosinophilic Cardiac Involvement Presenting With Left Ventricular Massive Thrombus and Cardioembolic Stroke: A Case Report
Introduction: It is well known that the tendency toward thrombosis is increased in cancer patients. The increase in cancer procoagulant and tissue factor levels, endothelial damage, and stasis due to compression are among the most accused causes of thrombosis in cancer patients. Hypereosinophilia is a rare condition that causes endothelial damage leading to thrombosis. <s...
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Purpose: Many patients with BRAFV600E mutant melanoma treated with BRAF inhibitors experience a rapid response, but ultimately develop resistance. Insight into the mechanism of resistance is critical for development of more effective treatment strategies.Experimental Design: Comprehensive genomic profiling of serial biopsies was performed in a patient with a BRAFV600E mutant metastatic melanoma...
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ژورنال
عنوان ژورنال: Journal of the National Comprehensive Cancer Network
سال: 2014
ISSN: 1540-1405,1540-1413
DOI: 10.6004/jnccn.2014.0065